• jorge luis

    Unique CD8 T cell-rich lymphoid aggregates in human uterine endometrium more. by jorge luis. ... Endometrium, Lymphoid Tissue, and Cell Aggregation Download (.pdf) • …

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  • Mucosal Immunity in the Human Reproductive Tract ...

     · Monocytes/macrophages (CD14 + cells) were found as a mantle around the T cells. The size of lymphoid aggregates was found to vary with the stage of the menstrual cycle (Yeaman et al., 1997). Aggregates were significantly larger during the secretory stage (3000–4000 cells) than those seen in uteri from women at the proliferative stage (300 ...

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  • A review of the human vs. porcine genital tract and ...

     · Yeaman GR, Wirat R, Guyre PM, Gonzalez J, Collins JE, Stern JE (1997) Unique CD8 T cell-rich lymphoid aggregates in human uterine endometrium. J Leukoc Biol 61:427–435. CAS PubMed Google Scholar 59.

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  • (PDF) Unique CD8 T cell-rich lymphoid aggregates in human ...

    Unique CD8 T cell-rich lymphoid aggregates in human uterine endometrium

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  • Composition, Development, and Function of Uterine …

    nancy (22, 25). Lymphoid aggregates (LA) mostly composed of noncytotoxic CD8+ T cells form regularly in the basal layer of the endometrium during the menstrual cycle in humans, although the origin and function of LA is unclear (26). In the mouse, the uterus is the most NK-rich organ in the body with uNK cells representing up to 50% of

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  • Prevalence of chronic endometritis in recurrent ...

     · Unique CD8+ T cell–rich lymphoid aggregates in human endometrium. J Leukoc Biol. 1997; 61 : 427-435 View in Article

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  • Endometritis: new time, new concepts

     · Unique CD8+ T cell-rich lymphoid aggregates in human endometrium. J Leukoc Biol. 1997; 61 : 427-435 View in Article

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  • The Role of Uterine NK Cells in Normal Reproduction and ...

    Yeaman GR, Guyre PM, Fanger MW, Collins JE, White HD, Rathbun W, Orndorff KA, Gonzalez J, Stern JE, Wira CR (1997) Unique CD8+ T cell-rich lymphoid aggregates in human uterine endometrium. J Leukoc Biol 61:427–435 PubMed Google Scholar

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  • Regulation of innate and adaptive immunity by the ...

    Unique CD8+ T cell-rich lymphoid aggregates in human uterine endometrium. J. Leukocyte Biol. 61, 427 – 435. Google Scholar. OpenURL Placeholder Text [59] Yeaman. G.R. et al. (2001) CD8+ T cells in human uterine endometrial lymphoid aggregates: evidence for accumulation of cells by trafficking.

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  • Dioxin may promote inflammation-related development of ...

    CD8+ T cells in human uterine endometrial lymphoid aggregates: evidence for accumulation of cells by trafficking. ... Unique CD8+ T cell-rich lymphoid aggregates in human uterine endometrium. J Leukoc Biol ... our experimental model of endometriosis has also provided unique information in regard to both human and murine cell behavior during the ...

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  • Differential Expression of Toll-Like Receptors 2 and 4 in ...

    In addition, Yeaman et al. demonstrated the existence of unique CD8 +-T-cell-rich lymphoid aggregates in human endometrium . In contrast, relatively little is known about innate immune responses within the human reproductive tract.

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  • Uterine leukocytes: key players in pregnancy.

     · Quantitative analysis of T lymphocyte subsets in pregnant and nonpregnant human endometrium. Vassiliadou N, Bulmer JN. Biol. Reprod., (5):1017-1022 MED: 8902212

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  • processing of human lymphoid aggregates

    Unique CD8 T cell-rich lymphoid aggregates in human uterine endometrium Jorge Gonzalez, cells in ice-cold PBS throughout processing to prevent internalization of sur- and an outer mantle of macrophag, lymphoid aggregate T cells were uniformly negative Our finding of LA development during the course of the for class II expression.

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  • Jorge Gonzalez

    Unique CD8 T cell-rich lymphoid aggregates in human uterine endometrium more. ... Unique CD8 T cell-rich lymphoid aggregates in human uterine endometrium more. by Jorge Gonzalez. ... Unique CD8 T cell-rich lymphoid aggregates in human uterine endometrium more.

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  • Evolution of non-cytotoxic uterine natural killer (uNK ...

    Yeaman GR, Guyre PM, Fanger MW, Collins JE, White HD, Rathbun W, Orndorff KA, Gonzalez J, Stern JE, Wira CR. Unique CD8 + T cell-rich lymphoid aggregates in human uterine endometrium. J Leukoc Biol. 1997; 61:427–435.

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  • Immunology of the Uterine and Vaginal Mucosae

     · Additionally, macrophages are involved in the formation of lymphoid aggregates and may participate in antigen presentation and in assisting CD8 + T and B cell activation. The function of the lymphoid aggregates in the human uterus is currently unclear, but they may be involved in antigen scavenging and antibody production.

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  • Unique CD8+ T cell-rich lymphoid aggregates in human ...

     · Using confocal scanning laser microscopy of viable tissue sections, we have demonstrated organized lymphoid aggregates (LA), that have a unique structure, in the stratum basalis of uterine endometrium. These LA consist of a core of B cells surrounded by more numerous T cells and an outer halo of monocytes/ macrophages.

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  • Immunology of the Uterine and Vaginal Mucosae

    Additionally, macrophages are involved in the formation of lymphoid aggregates and may participate in antigen presentation and in assisting CD8 + T and B cell activation. The function of the lymphoid aggregates in the human uterus is currently unclear, but they may be involved in antigen scavenging and antibody production.

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  • Uterine stem cells: What is the evidence? | Human ...

    Adult stem cells are defined by their functional properties rather than by marker expression. Evidence for the existence of adult stem/progenitor cells in human and mouse endometrium is now emerging because functional stem cell assays are being applied to uterine cells and tissues.

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  • Unique CD8 + T cell‐rich lymphoid aggregates in human ...

    Unique CD8 T cell-rich lymphoid aggregates in human uterine endometrium ... Yeaman et al. Unique human uterine lyniphoid aggregates 429 CD no. CD3 CD3 CD4 CD4 CD8 CD8 CD14 CD14 CD I 9 CDI9 CD37 CD56 CD66b Clone 4.1 OKT3 S3.5 OKT4 3B5 OKT8 TUK 4 AML-223 SJ25-Ci FMC63 WR17 562 531 Ber EP4 F8i 7 IVA12 P3 Supplier

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  • Immunomorphologic studies of human decidua-associated ...

    They are present in aggregates [lymphoid cell clusters (LCC) mainly located in the vicinity of decidual/endometrial glands] and as individual cells, intra- or subepithelially along the glands (IEL), and in the stroma. The LCC appear to be centres of immune reactivity. They occur at a frequency of 0.4 0.2/mm 2 tissue and are composed of ...

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  • Jorge Gonzalez

    Unique CD8 T cell-rich lymphoid aggregates in human uterine endometrium more. by Jorge Gonzalez. Research Interests: Immunology, Humans, , Menstrual Cycle, Phenotype, and 6 more Aged, Middle Aged, Adult, Confocal Laser Scanning Microscopy, Endometrium, and Lymphoid Tissue

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  • Uterine Natural Killer Cells: Functional Distinctions and ...

    We also review how uNK cells may regulate tro-phoblast invasion and uterine spiral arterial remodeling in human and murine pregnancy. Keywords: uterine natural killer cells, uterine innate lymphoid cells, placenta, pregnancy, arterial remodeling, iNTRODUCTiON CD56 uterine natural killer (uNK) cells are present in human endometrium prior to the

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  • Composition, Development, and Function of Uterine Innate ...

    nancy (22, 25). Lymphoid aggregates (LA) mostly composed of noncytotoxic CD8+ T cells form regularly in the basal layer of the endometrium during the menstrual cycle in humans, although the origin and function of LA is unclear (26). In the mouse, the uterus is the most NK-rich organ in the body with uNK cells representing up to 50% of

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  • CORE

    Unique CD8+ T cell-rich lymphoid aggregates in human uterine endometrium. (2004). Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta.

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  • Immune Reconstitution of the Reproductive Tract of ...

    Memory CD4 + and CD8 + T cells represent the majority of the T cells found in the intestines, only a few naïve T cells are present. The fact that human lymphoid reconstitution extends to the distal end of the lower GI tract renders BLT mice susceptible to rectal HIV-1 transmission that, like described above for humans, results in CD4 + T cell ...

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  • Innate Lymphoid Cells in Mucosal Immunity

     · Neuropilin-1 is expressed on lymphoid tissue residing lti-like group 3 innate lymphoid cells and associated with ectopic lymphoid aggregates. Cell Rep. (2017) 18 :1761–73. 10.1016/j.celrep.2017.01.063 [ PMC free article ] [ PubMed ] [ CrossRef ] [ Google Scholar ]

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  • (PDF) Unique CD8 T cell-rich lymphoid aggregates in human ...

    Unique CD8 T cell-rich lymphoid aggregates in human uterine endometrium Grant R. Yeaman,* Paul M. Guyre,t Michael W. Fanger,* Jane E. Collins,* Hillary D. White,* Wayne Rathbun Kenneth A. Orndorff,t Jorge Gonzalez,t Judy E. Stern, and Charles R. Wirat *Depajrtment of Microbiology, t Physiology, 1 Pathology, and § Obstetrics & Gynecology, Dartmouth Medical School, Lebanon, New Hampshire ...

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  • Proliferative activity of lymphoid cells in human ...

    Human endometrium harbors a major population of lymphoid cells. The proliferation of these cells is assessed by the in situ labeling of endometrial sections for Ki67 (a proliferation marker) as well as in vitro incorporation of bromodeoxyuridine (BrdU; a thymidine analog) into S-phase cells in vibratome sections of endometria. Using the avidin-biotinperoxidase complex method, sections of ...

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  • Highly-Exposed HIV-1 seronegative Commercial ...

     · Yeaman, G. R. et al. Unique CD8 + T cell-rich lymphoid aggregates in human uterine endometrium. J Leukoc Biol 61, 427–435 (1997). CAS Article PubMed Google Scholar

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  • Immune responses in the human reproductive tract ...

     · Innate lymphoid cells and innate‐like T‐cells in the vagina. In addition to APCs, several innate and innate‐like lymphocyte populations contribute to immune surveillance and protection of the lower FRT. Natural killer (NK) cells, which are members of the innate lymphoid cell (ILC) family, 30 are present in the vagina.

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  • Frontiers | Tertiary Lymphoid Structures in Cancers ...

     · They display an overall organization similar to that observed in canonical secondary lymphoid organs (SLOs), such as lymph nodes (LNs), with a T cell-rich area characterized by a T cell and mature DC-Lamp + dendritic cell (DCs) cluster, a B-cell-rich area composed of a mantle of naïve B cells surrounding an active germinal center (GC) (1–3 ...

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